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Enzyme Design — Pre-Seed
Offered To Invest Fund: StoryHouse Fund II  ·  SH Check: $800,000  ·  Valuation: $16M
Dossier generated 2026-05-27 by /deal-dossier  ·  Deal record: recPXDMwUU6cH4CfF  ·  Source: Airtable appjxAR3LPe3fkHOp

One-Liner & Thesis

ML design of enzyme therapies. Enzyme Design operates in Biotech; this dossier captures the Pre-Seed we participated in.

$6M round on a $10M Pre Priced Round with Amplify as the Lead SH committed $800,000, via StoryHouse Fund II, at a $16M valuation, in a $6M round, alongside Third Rock Ventures, Amplify Partners.

Deal Box

Round Size
$6M
Valuation / Cap
$16M
Co-Investors
Third Rock Ventures, Amplify Partners
SH Check
$800,000
Fund
StoryHouse Fund II
Funding Round
Pre-Seed

Company Snapshot

Sector
Biotech
Location
Bay Area, California
Year Founded
2024-03-01
Website
NA
Status
Private

Founders

Aaron Arvey
Founder/team member at Enzyme Design.
Andrea Van Elsas
Founder/team member at Enzyme Design.
Matthew Ravalin
Founder/team member at Enzyme Design.

Latest Meeting Notes

2026-04-06 — DeaL Call Notes - 2026-04-06

KH Notes: ___________ M&K with Aaron \### Round Status • Lawyers (Goodwin for Enzyme Co, Cooley for Amplify) exchanging drafts; currently stuck on drag-along rights • First draft shared from Goodwin to Cooley; Cooley reviewing, expected back by end of this week • Target close: April 24 or end of following week — strong preference to avoid slippi…

Source: Meeting Notes reczrWvQbwAsRYAjW

2026-03-05 — Deal Notes - 2026-03-05

Elliot Hershberg is the partner at Amplify who is leading the Seed round for Enzyme Design. <https://www.amplifypartners.com/team/elliot-hershberg>

Source: Meeting Notes reclnbQfq3nMkFwJJ

2026-02-24 — Reference Call Notes - 2026-02-24

Source: Meeting Notes recL6GCQXJaLb6jqR